This article summarizes the David Sun Lecture at the American College of Gastroenterology in Orlando, Florida, that was delivered on October 4, 2008. The lecture, entitled “The Future Direction of IBD Care,” reviewed the future use of current drugs (such as 5-aminosalicylate, steroids, immunosuppressive medications, and biologic agents) and upcoming drugs in the treatment of IBD.[Rev Gastroenterol Disord. 2009;9(3):E69-E77 doi: 10.3909/rigd0350]

Antimicrobial resistance is a major cause for failed Helicobacter pylorieradication. This article discusses the prevalence and mechanisms ofresistance in harboring resistant strains.H pylori and presents a strategy for eradication in patients[Rev Gastroenterol Disord. 2009;9(3):E78-E83 doi:10.3909/rigd0352]

Constipation is a common problem associated with opiates and opioidcompounds used for the treatment of pain and other medical conditions, andcan influence patient quality of life. Methylnaltrexone appears effective in thetherapy of opioid-induced constipation and will be useful for patients failingto respond to traditional laxative regimens.[Rev Gastroenterol Disord. 2009;9(3):E84-E93 doi: 10.3909/rigd0346]